Alanine Dosimetry System

Industry standard for evaluating irradiation doses on alanine pellets or blisters.

MiniScope MS 5000 EPR spectrometer is a complete alanine-EPR dosimetry system for routine dosimetry in industrial irradiation facilities, or for use as an in-house alanine reference dosimetry system.

Benefits of MS 5000 - Alanine Dosimetry System

Highest quality measurements: the MS 5000 EPR instrument provides a stronger measurement response signal than any other bench-top EPR spectrometer on the market today, with higher measurement sensitivity.
Cuts measurement time in half: the MS 5000 EPR system reduces measurement times in half, from 40 seconds down to 10 seconds or less.
Reliability: the new EPR spectrometer uses a solid-state technology, to provide a more rugged industrial instrument for higher reliability and uptime > 99 %.
Flexibility: Accommodates a wide variety of commercially available alanine dosimeters with specialized holders.
Remote accessibility: IP based system allows remote operation and technical support from anywhere in the world.

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Straightforward and quick measurement

Alanine is an amino acid forming a very stable free radical when subjected to ionizing radiation. The alanine free radical yields an EPR signal with an amplitude that is dose dependent (Fig.1).

The measurement time of the MS 5000 is very short and depends on the dose.

High dose0.5 up to > 200 kGy10 s, approx. 8000 readouts a day
Low dose<1 up to 20 Gy120 s


The MS5000 is calibrated one time in a very simple procedure and with a large calibration range (Fig.2) and afterwards only a very straightforward and quick measurement routine needs to be performed by the user.



Fig.1: Example of a typical measured EPR spectrum for alanine samples, which were irradiated with different doses
Fig.2: Typical calibration curve

Alanine dosimeters

The alanine free radical yields an EPR signal that is dose dependent. The MS 5000 EPR spectrometer is a simple, fast and accurate measurement equipment for alanine dosimetry for either pellets or blisters.

Glassware and optional add ons

  • Alanine pellets

  • Alanine pellet holder

  • Alanine blisters

  • Alanine blister holder

  • Barcode reader

  • Autosampler

  • Special alanine dosimetry software

Contact us for more information.

Special application notes

Decomposition study of irradiated alanine

Recent Electron Paramagnetic Resonance (EPR) and Electron Nuclear Double Resonance (ENDOR) studies on irradiated alanine powder showed the presence of three radicals contributing to alanine's total EPR spectrum.

Study on relaxation rates of stable paramagnetic centers in γ-irradiated alanine

The stable L-alanine radical induced by γ-irradiation was examined by electron paramagnetic resonance (EPR), transfer saturation EPR and electron nuclear double resonance (ENDOR) in the temperature region of fast motionof the methyl group (180–320 K). From the obtained spectral line broadening and intensity the correlation time for the methyl rotation was estimated.