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Electrical semiconductor characterization
Luminescence dating, research, dosimetry and more
Free radical measurements in life science and biomedical applications
Our benchtop MiniScope (MS 5000) ESR spectrometer is a research grade device with sensitivity and reliability for demanding...
Nitric oxide measurement, reactive oxygen species, oxidative stress, radical generating systems, photo dynamic therapy
Bioinorganic transition metal compounds, fenton chemistry, effect of heavy metal ions on livving tissue
Antioxidative features of foodstuff, radicals on foodstuff, radiation-induced radicals
Living polymers, nitroxide quantification, radicals in varnish, UV stability of scratch resistant varnish
Industry standard for evaluating irradiation doses on alanine tablets
Oxymetry, membrane fluidity, pH in microenvironment, viscosity, phase partition
Variety of free radicals in environmental applications can be evaluated by EPR spectroscopy
Beer flavor stability and shelf time evaluation
Analysis of chemical structure of paramagnetic centers and their orientation within a crystal
ESRStudio is a dynamic and user friendly software for ESR measurements with some of the most modern and fluent workflow based...
Magnettech GmbH was founded in 1991 by the members of the department of "Centre for Construction of Scientific Devices"...
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Structural elucidation studies are a classical field of application for the MS5000 in combination with autosampler. ESR spectroscopy contributes in a different way to many areas such as biophysics wherever radicals may play a chemical role or may be used as labels or probes. Since this spectroscopic method is able to „see“ the unpaired electron, and nothing else, it is an unique way to detect and measure radicals directly. Minimum requirement is the presence of a sufficiently high concentration of radicals, due to the high sensitivity of miniscope 5000 ESR spectrometer reaching down to nanomolar range.
Depending on the specific problem to be solved different methods of measuring radicals are available which are presented with the help of practical examples:
Radicals induced by radiation can be detected directly even at reactions speeds down to 2µs due to the high speed kinetic option of the MS5000.
Radicals derived from dry alanine powder persist for very long periods this material can be used efficiently for dosimetry.
Radical existing only for a short period may be trapped by so-called spin traps. The unpaired electron is preserved for measurement in an adduct compound of the spin trap as a standard application for MS5000 EPR spectrometer
Certain radicals stable for a long time period, so-called spin labels, can be used as probes for the fluidity or viscosity of the phase environmental to the unpaired electron.
Since the line width in a spectrum of a spin label depends on the content of molecular oxygen within the sample this effect can be used to quantify oxygen (oximetry).
In the absence of water radicals induced by radiation will survive for months, even years. The existence of radicals in dried food (e.g. spices) can proof radiation treatment. Another practical application of measuring radiation induced radicals is alanine dosimetry.
Since radicals are the agents making oils and fats rancid antioxidative substances are of broad interest as protective additives within the food and cosmetic industry. The efficiency of such additives are tested MS5000 EPR spectroscopy after incubation with reactive radicals. Four routine applications combination of ESR spectrometer with autosampler makes it an efficient equipment for high throughput.