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Electrical semiconductor characterization
Luminescence dating, research, dosimetry and more
Free radical measurements in life science and biomedical applications
Our benchtop MiniScope (MS 5000) ESR spectrometer is a research grade device with sensitivity and reliability for demanding...
Industry standard for evaluating irradiation doses on alanine tablets
Nitric oxide measurement, reactive oxygen species, oxidative stress, radical generating systems, photo dynamic therapy
Antioxidative features of foodstuff, radicals on foodstuff, radiation-induced radicals
Analysis of chemical structure of paramagnetic centers and their orientation within a crystal
Bioinorganic transition metal compounds, fenton chemistry, effect of heavy metal ions on livving tissue
Variety of free radicals in environmental applications can be evaluated by EPR spectroscopy
ESRStudio is a dynamic and user friendly software for ESR measurements with some of the most modern and fluent workflow based...
Magnettech GmbH was founded in 1991 by the members of the department of "Centre for Construction of Scientific Devices"...
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Epidemiological studies have demonstrated the relationship between exposure to ambient particulate matter (PM) and health effects in those with cardiopulmonary diseases. The free radical generating activity of particles has been suggested as a unifying factor in the biological activity of PM in toxicological studies but so far has not been applied as a method for environmental monitoring of PM. The purpose of this study was to characterize hydroxyl radical (OH?) production by different size fractions of PM, to use as an alternative method for monitoring of PM composition and activity. We have developed a method, using electron paramagnetic resonance (EPR), to measure OH? radical formation in suspensions of particles in the presence of hydrogen peroxide and 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) as a speciﬁc spin-trap. Samples of ambient particulate matter (PM) of different size fractions were collected from various sites on various ﬁlters. PM deposited on ﬁlters as well as suspensions in water retain its ability to generate OH? and this generation is determined by concentration of hydrogen peroxide and soluble metals. However, large variations in OH? radical formation and kinetics were found with different soluble metals and within metals (Fe, V) with different valencies. The method was applied to environmental monitoring in Hettstedt-Zerbst, situated in South-Eastern Germany, where it showed a relation to Cu-content of PM. The method was also applied in Duisburg, where the PM1 fraction showed the highest DMPO–OH? generation but was not linked to particle counts. The method integrates metal bioavailability and reactivity and can provide a better understanding of the effect of small variations in mass concentrations on health.