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Electrical semiconductor characterization
Luminescence dating, research, dosimetry and more
Free radical measurements in life science and biomedical applications
Our benchtop MiniScope (MS 5000) ESR spectrometer is a research grade device with sensitivity and reliability for demanding...
The MS 6000 is a research device with high-end sensitivity for sophisticated applications in field of science & technology.
Industry standard for evaluating irradiation doses of alanine pellets and blisters
Nitric oxide measurement, reactive oxygen species, oxidative stress, Proteine structure & enzyme function
Antioxidative features of foodstuff, Food irradiation control, Flavour stability, Beer analysis
Analysis of chemical structure of paramagnetic centers and their orientation within a crystal
A variety of free radicals is formed through pollutants such as particulate matter, nanoparticles or others
Asphaltenes in crude oil, Thermooxidative breakdown of lubricants, Polymerization control
Quality control of pharmaceuticals and impurity profiling
Spin density, Kinetic measurements
ESRStudio is a dynamic and user friendly software for ESR measurements with some of the most modern and fluent workflow based...
Magnettech GmbH was founded in 1991 by the members of the department of "Centre for Construction of Scientific Devices"...
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Spin trapping technique using MS5000 EPR/ESR spectrometer is a standard application to determine the oxygen concentration in living tissue.
EPR signals are broadened with increasing oxygen concentration. Appliyng a apramagnetic oxygen sensor, the measurement of local quantities of oxygen is carried out within minutes. Suspensions of charcoal allow observation at any place a liquid could reach.
Results of tumor oxygenation
Bernard Gallez, Bénédicte F. Jordan, Nicolas Christian, Nathalie Crokart, Vincent Grégoire, Olivier Feron (2007) - Thyroid Status is a Key Modulator of Tumor Oxygenation: Implication for Radiation Therapy. Radiation Research 168, 428-432
Gallez et al. (2007) name the rate of oxygen consumption as a "key factor" to estimate the effect of radiation therapy on tumor cells. In healthy tissue, hormones such as thyroid stimulate oxygen consumption. Therefore, an analogous effect on tumors was hypothezised.
Experimental tumors and their close environment were observed to see if changes in the thyroid concentration effects their metabolic activity. EPR oximetry revealed a significant change of the oxygen concentration with varying thyroid status. Thus, oxygen consumption was altered tremendously. As expected, tumor's regrowth was dealyed by lowering thyroid activity.
"This study provides unique insights into the impact of modulating tumor oxygen consumption and could have implications in the management of cancer patients with thyroid disorders."