Applications of EPR Spectroscopy

MiniScope, Benchtop EPR Spectrometers

Life Sciences

• The only method for direct Nitric Oxide (NO) Measurement
  • Quantification of vascular nitric oxide (NO)
  • Quantification of NO in cells and tissue
  • Quantification of NO in blood
  • Quantification of NO-haemoglobin
• Reactive Oxygen Species (ROS) and Oxidative Stress
  • Quantification of reactive oxygen species (ROS) in cells, tissue, blood
  • Quantification of ascorbyl radicals in blood plasma
  • Singlet oxygen and hydroxyl radicals in photo dynamic therapy (PDT)
  • Superoxide generated by xanthine / xanthine oxidase

Food Chemistry and Pharmacy

• Radicals generated during sterilisation by gamma irradiation
• Quantification of the antioxidative activity
• Quantification of the antioxidative potential
• Radicals and copper in hop
• Radicals in Malt
• Radicals in Coffee Powder
• Flavour stability of coffee
• Antioxidative features of margarine

Petrol Chemistry

• Determination of nitroxide concentrations in unsaturated hydrocarbons
• Living polymers
• UV stability of scratch resistant varnish
• Electron beam hardening of varnish

Environmental Toxicology

• Generation of radicals by particles

Dosimetry

• Alanine dosimetry (thin films + tablets)

Biophysical Features

• Oxymetry
• Membrane fluidity
• pH-measurement
• Viscosity
• Phase partition

Separation of Radicals

• EPR/HPLC coupling

Bioinorganic Chemistry

• Bioinorganic transition metal compounds
• Effect of heavy metals ions on living tissue

Tomography

• PH-profiles in human skin
• Liposomal penetration into human skin
• Spectral-spatial imaging

Spectral Measurements (L-band)

• Oxymetry
• Dosimetry